Get Started On Bcl-2 Family Proteins: Methods And Protocols Narrated By Evripidis Gavathiotis Presented As Paper Edition

volume explores numerous techniques for the genetic, molecular, biochemical, and structural examination of BCLfamily proteins and their interactions, The chapters in this book cover topics such as the relevance of BCLproteins in health and disease evaluating cellular dependencies to specific BCLfamily proteins flowcytometrybased methods for measuring BCLproteins and mitochondrialbased cell death measuring activity and interactions of BCLfamily proteins in the presence of mitochondria, artificial membranes or yeast conformational activation and oligomerization of proapoptotic proteins BAX and BAK leading to cytochrome c release and apoptosis structural and biophysical studies in solution and lipid vesicles using nuclear magnetic resonance, cryoelectron microscopy, fluorescence microscopy and electron paramagnetic resonance.
Written in the highly successful Methods in Molecular Biology series

format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, stepbystep, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.




Cuttingedge and thorough, BCLFamily Proteins: Methods and Protocols is a valuable resource to inspire and encourage novice and established scientists to further their research and make new discoveries in this exciting field.

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